Message: 20
Date: Thu, 3 Feb 2005 20:17:55 -0500
From: "Robert MacPherson"
Subject: Press Release: U-M Scientists Develop First Micro-Machined
Cochlea
The University of Michigan news service, Feb. 2, 2005
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U-M scientists develop first micro-machined mechanical cochlea
ANN ARBOR, Mich.—Scientists at U-M have developed the first
micro-machined, life-sized, mechanical
cochlea, the tiny organ responsible for converting acoustic vibrations
into electrical signals for
the brain to "read" and interpret as different sounds.
Most people with hearing loss have lost the ability to translate
acoustic sound waves into
electrical signals for the brain, so developing a device capable of
simulating this function is an
important step in the effort to help at least some of the estimated 560
million people who will
experience hearing loss by this year. While the U-M system is not yet
ready for use as an implant,
the 3-centimeter device could potentially be used as part of a cochlear
implant. More immediate
applications include a low-power sensor for military or commercial
applications, said College of
Engineering associate professor Karl Grosh.
The three advantages of the mechanical cochlea built at U-M are its
life-sized dimensions, its
suitability for mass production, and its use of a unique low-power
mechanical method to do acoustic
signal processing, Grosh said. The human cochlea is a snail-shaped
organ measuring about a cubic
centimeter in the inner ear. If you unwind the spiral, it would equal
the length of the U-M
mechanical cochlea. Researchers micro-machined the device using a
technique similar to those used to
make integrated circuits, which means it can be mass produced.
The mechanical cochlea works in the same way as its biological
counterpart. In the biological
cochlea, the basilar membrane, which winds along the cochlear spiral,
is stiffer at the base and
becomes softer as it approaches the center. In the engineered cochlea
developed by Grosh and
doctoral student Robert White, a fluid-filled duct etched onto a chip
acts as the cochlear spiral.
When sound waves enter the mechanical cochlea's input membrane, a wave
is created, which travels
down the duct, interacting with a tapered micro-machined membrane,
analogous to the basilar
membrane. This process allows the device to separate different
frequency tones. In the biological
cochlea, sensory hair cells in the spiral detect the sound waves
traveling through the fluid, and
translate the sound waves into electrical signals, which the auditory
nerve carries to the brain.
The ear hears different sounds depending on where the wave vibrates in
the cochlea.
The goal is to use the mechanical cochlea as a sensitive microphone,
perhaps in tandem with a
cochlear implant, Grosh said, the same way an external microphone, a
microprocessor and an antenna
work together in present implants. Cochlear implants work by sending
signals for different
frequencies to electrodes implanted in the cochlear spiral. The
auditory nerves then transport these
signals to the brain. Researchers are adding arrays of sensors to the
mechanical cochlea, which
would make it possible to use the new device to drive the electrodes in
a cochlear implant.
Grosh and White co-authored a paper "Microengineered Hydromechanical
Cochlear Model," which appeared
in the Proceedings of the National Academy of Sciences, Feb. 1, 2005.
The work is primarily funded by the National Science Foundation and the
Office of Naval Research.
The University of Michigan College of Engineering is ranked among the
top engineering schools in the
country. Michigan Engineering boasts one of the largest research
budgets of any public university,
at $135 million for 2004. Michigan Engineering has 11 departments and
two NSF Engineering Research
Centers. Within those departments and centers, there is a special
emphasis on research in three
emerging industries: Nanotechnology and integrated microsystems;
cellular and molecular
biotechnology; and information technology. The College is seeking to
raise $110 million for capital
building projects and program support in these areas to further
research discovery. The CoE's goal
is to advance academic scholarship and market cutting edge research to
improve public heath and
well-being.